[Postmortem diagnosis of tropical malaria].
Identifieur interne : 000572 ( Main/Exploration ); précédent : 000571; suivant : 000573[Postmortem diagnosis of tropical malaria].
Auteurs : S. Albert ; A. Schröter ; H. Bratzke ; V. BradeSource :
- Deutsche medizinische Wochenschrift (1946) [ 0012-0472 ] ; 1995.
Descripteurs français
- KwdFr :
- Adulte, Allemagne, Autopsie, Diagnostic différentiel, Encéphale (anatomopathologie), Foie (anatomopathologie), Humains, Issue fatale, Kenya, Myocarde (anatomopathologie), Mâle, Paludisme cérébral (anatomopathologie), Paludisme à Plasmodium falciparum (anatomopathologie), Parasitémie (anatomopathologie), Poumon (anatomopathologie), Rate (anatomopathologie), Rein (anatomopathologie), Voyage.
- MESH :
- anatomopathologie : Encéphale, Foie, Myocarde, Paludisme cérébral, Paludisme à Plasmodium falciparum, Parasitémie, Poumon, Rate, Rein.
- Adulte, Allemagne, Autopsie, Diagnostic différentiel, Humains, Issue fatale, Kenya, Mâle, Voyage.
- Wicri :
English descriptors
- KwdEn :
- Adult, Autopsy, Brain (pathology), Diagnosis, Differential, Fatal Outcome, Germany, Humans, Kenya, Kidney (pathology), Liver (pathology), Lung (pathology), Malaria, Cerebral (pathology), Malaria, Falciparum (pathology), Male, Myocardium (pathology), Parasitemia (pathology), Spleen (pathology), Travel.
- MESH :
- geographic : Germany, Kenya.
- pathology : Brain, Kidney, Liver, Lung, Malaria, Cerebral, Malaria, Falciparum, Myocardium, Parasitemia, Spleen.
- Adult, Autopsy, Diagnosis, Differential, Fatal Outcome, Humans, Male, Travel.
Abstract
Thirteen days after returning from a four week holiday in Kenya a 35-year-old man consulted his doctor complaining of feeling unwell. The doctor diagnosed influenza and gave him a sickness certificate for three days. Because the patient did not reappear at his workplace a search was made and he was found dead in his flat seven days after seeing his doctor. A medicolegal autopsy was performed two days after the estimated time of death. There was marked swelling of liver and spleen together with jaundice and "dirty grey" colouration of the viscera. Samples of heart blood and spleen puncture material were taken. Giemsa stained preparations (ordinary and thick blood smears) revealed numerous objects 1.2 to 1.5 microns in size with indistinct reddish blue staining, some of them arranged in rosettes reminiscent of schizonts. A few of them contained pigment. In material from the spleen there were masses of blackish-brown pigment. The malaria immunofluorescence test performed on serum gave a weakly positive titre of 1:40. The findings were considered enough to support a diagnosis of fulminant falciparum malaria, and this was confirmed by histological changes in various organs, notably the typical capillary blockages in the brain. Because of the popularity of long-haul tourism, cases of imported malaria are increasingly frequent and, in view of the insidiously progressive course of the disease, it should always be considered in the differential diagnosis. In cases of unexplained death, if there is any suspicion of malaria, blood should always be taken for appropriate investigations, in addition to blocks for histological examination.
DOI: 10.1055/s-2008-1043193
PubMed: 7821199
Affiliations:
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Le document en format XML
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Brade</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1995">1995</date><idno type="RBID">pubmed:7821199</idno><idno type="pmid">7821199</idno><idno type="doi">10.1055/s-2008-1043193</idno><idno type="wicri:Area/Main/Corpus">000590</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000590</idno><idno type="wicri:Area/Main/Curation">000590</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000590</idno><idno type="wicri:Area/Main/Exploration">000590</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Postmortem diagnosis of tropical malaria].</title><author><name sortKey="Albert, S" sort="Albert, S" uniqKey="Albert S" first="S" last="Albert">S. Albert</name><affiliation><nlm:affiliation>Abteilung für Medizinische Mikrobiologie im Zentrum der Hygiene sowie Zentrum der Rechtsmedizin, Klinikum der Universität Frankfurt/Main.</nlm:affiliation><wicri:noCountry code="subField">Klinikum der Universität Frankfurt/Main</wicri:noCountry></affiliation></author><author><name sortKey="Schroter, A" sort="Schroter, A" uniqKey="Schroter A" first="A" last="Schröter">A. Schröter</name></author><author><name sortKey="Bratzke, H" sort="Bratzke, H" uniqKey="Bratzke H" first="H" last="Bratzke">H. Bratzke</name></author><author><name sortKey="Brade, V" sort="Brade, V" uniqKey="Brade V" first="V" last="Brade">V. 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The doctor diagnosed influenza and gave him a sickness certificate for three days. Because the patient did not reappear at his workplace a search was made and he was found dead in his flat seven days after seeing his doctor. A medicolegal autopsy was performed two days after the estimated time of death. There was marked swelling of liver and spleen together with jaundice and "dirty grey" colouration of the viscera. Samples of heart blood and spleen puncture material were taken. Giemsa stained preparations (ordinary and thick blood smears) revealed numerous objects 1.2 to 1.5 microns in size with indistinct reddish blue staining, some of them arranged in rosettes reminiscent of schizonts. A few of them contained pigment. In material from the spleen there were masses of blackish-brown pigment. The malaria immunofluorescence test performed on serum gave a weakly positive titre of 1:40. The findings were considered enough to support a diagnosis of fulminant falciparum malaria, and this was confirmed by histological changes in various organs, notably the typical capillary blockages in the brain. Because of the popularity of long-haul tourism, cases of imported malaria are increasingly frequent and, in view of the insidiously progressive course of the disease, it should always be considered in the differential diagnosis. In cases of unexplained death, if there is any suspicion of malaria, blood should always be taken for appropriate investigations, in addition to blocks for histological examination.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">7821199</PMID><DateCompleted><Year>1995</Year><Month>02</Month><Day>14</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0012-0472</ISSN><JournalIssue CitedMedium="Print"><Volume>120</Volume><Issue>1-2</Issue><PubDate><Year>1995</Year><Month>Jan</Month><Day>05</Day></PubDate></JournalIssue><Title>Deutsche medizinische Wochenschrift (1946)</Title><ISOAbbreviation>Dtsch. Med. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Postmortem diagnosis of tropical malaria].</ArticleTitle><Pagination><MedlinePgn>18-22</MedlinePgn></Pagination><Abstract><AbstractText>Thirteen days after returning from a four week holiday in Kenya a 35-year-old man consulted his doctor complaining of feeling unwell. The doctor diagnosed influenza and gave him a sickness certificate for three days. Because the patient did not reappear at his workplace a search was made and he was found dead in his flat seven days after seeing his doctor. A medicolegal autopsy was performed two days after the estimated time of death. There was marked swelling of liver and spleen together with jaundice and "dirty grey" colouration of the viscera. Samples of heart blood and spleen puncture material were taken. Giemsa stained preparations (ordinary and thick blood smears) revealed numerous objects 1.2 to 1.5 microns in size with indistinct reddish blue staining, some of them arranged in rosettes reminiscent of schizonts. A few of them contained pigment. In material from the spleen there were masses of blackish-brown pigment. The malaria immunofluorescence test performed on serum gave a weakly positive titre of 1:40. The findings were considered enough to support a diagnosis of fulminant falciparum malaria, and this was confirmed by histological changes in various organs, notably the typical capillary blockages in the brain. Because of the popularity of long-haul tourism, cases of imported malaria are increasingly frequent and, in view of the insidiously progressive course of the disease, it should always be considered in the differential diagnosis. In cases of unexplained death, if there is any suspicion of malaria, blood should always be taken for appropriate investigations, in addition to blocks for histological examination.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Albert</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Abteilung für Medizinische Mikrobiologie im Zentrum der Hygiene sowie Zentrum der Rechtsmedizin, Klinikum der Universität Frankfurt/Main.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schröter</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Bratzke</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Brade</LastName><ForeName>V</ForeName><Initials>V</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><VernacularTitle>Postmortale Diagnose einer Malaria tropica.</VernacularTitle></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Dtsch Med Wochenschr</MedlineTA><NlmUniqueID>0006723</NlmUniqueID><ISSNLinking>0012-0472</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001344" MajorTopicYN="N">Autopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001921" MajorTopicYN="N">Brain</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017809" MajorTopicYN="N">Fatal Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007630" MajorTopicYN="N" Type="Geographic">Kenya</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007668" MajorTopicYN="N">Kidney</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016779" MajorTopicYN="N">Malaria, Cerebral</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016778" MajorTopicYN="N">Malaria, Falciparum</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009206" MajorTopicYN="N">Myocardium</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018512" MajorTopicYN="N">Parasitemia</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013154" MajorTopicYN="N">Spleen</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014195" MajorTopicYN="N">Travel</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1995</Year><Month>1</Month><Day>5</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1995</Year><Month>1</Month><Day>5</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1995</Year><Month>1</Month><Day>5</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">7821199</ArticleId><ArticleId IdType="doi">10.1055/s-2008-1043193</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Albert, S" sort="Albert, S" uniqKey="Albert S" first="S" last="Albert">S. Albert</name><name sortKey="Brade, V" sort="Brade, V" uniqKey="Brade V" first="V" last="Brade">V. Brade</name><name sortKey="Bratzke, H" sort="Bratzke, H" uniqKey="Bratzke H" first="H" last="Bratzke">H. Bratzke</name><name sortKey="Schroter, A" sort="Schroter, A" uniqKey="Schroter A" first="A" last="Schröter">A. Schröter</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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